abstract：AIM:To compare efficacy of basic RA treatment with methotrexate+plaquenil and basic monotherapy with methotrexate. MATERIAL AND METHODS:Two groups of rheumatoid arthritis (RA) patients were studied: group 1 (n = 82) received combined basic treatment with methotrexate (7.5 mg/week) in combination with plaquenil (0.2 ?m...

journal_title：Terapevticheskii arkhiv

authors： Sergiets NA,Erov NK

更新日期：2009-01-01 00:00:00

abstract：AIM:To study whether life quality (LQ) indices may be used to evaluate the efficiency of structural resonance electromagnetic therapy (SREMT) and its correction in patients with rheumatoid arthritis (RA) and in those with osteoarthrosis (OA). SUBJECTS AND METHODS:One hundred and twenty patients with significant RA and...

journal_title：Terapevticheskii arkhiv

authors： Grekhov RA,Aleksandrov AV,Alekhina IIu,Zborovskiĭ AB

更新日期：2009-01-01 00:00:00

abstract：AIM:To study the effects of enalapril and telmisartan on hemodynamic parameters and diastolic function (DF) of the left ventricle (LV) in patients with type 2 diabetes mellitus (DM) concurrent with arterial hypertension (AH). SUBJECTS AND METHODS:The study included 64 patients (mean age 54.3 +/- 5.2 years) with type 2...

journal_title：Terapevticheskii arkhiv

authors： Tatarchenko IP,Pozdniakova NV,Mordovina AG,Morozova OI,Zaĭtseva AV

更新日期：2009-01-01 00:00:00

abstract：:A case of the immunoglobuline deposit disease diagnosis in MM patient having the symptoms of intensive proteinuria, macrohematuria and terminal renal failure is reported. The disease was diagnosed by the evidence from electron microscopy of the kidney and liver biopsies. ...

journal_title：Terapevticheskii arkhiv

authors： Gorchakova SV,Rekhtina IG,Iatskov KV,Sukhanova GA,Golitsina EP,Varshavskiĭ VA,Biriukova LS

更新日期：2009-01-01 00:00:00

abstract：AIM:To investigate a clinicopathogenetic role of fibrinolysis regulators in chronic viral hepatitis (CVH) and viral cyrrhosis of the liver (CL). MATERIAL AND METHODS:Seventy patients entered the study: 10 patients with CVH B, 33--with CVH C, 6--with CVH D, 21--with viral CL (HCV-associated in 14 cases and HBV-associat...

journal_title：Terapevticheskii arkhiv

authors： Iagoda AV,Koroĭ PV

更新日期：2009-01-01 00:00:00

abstract：AIM:To analyse clinical implications of chromosome 8 trisomy in Ph-negative cells of the bone marrow in patients with chronic myeloid leukemia (CML) treated with inhibitors of tyrosinkinases (ITK). MATERIAL AND METHODS:A total of 386 patients with CML (chronic phase--288, acceleration phase--77) received imatinib (400...

journal_title：Terapevticheskii arkhiv

authors： Turkina AG,Domracheva EV,Vorontsova AV,Aseeva EA,Vinogradova OIu,Stakhina OV,Gusarova GA,Diagileva OA,Semenova EA,Vakhrusheva MV,Kolosheĭnova TI,Abakumov EM,Chelysheva EIu,Goriacheva SR,Ivanova TV,Zakharova ES,Kolosova LI

更新日期：2009-01-01 00:00:00

abstract：AIM:To characterize correlations between the levels of vitamin D, parathormone, calcium, blood phosphates in patients with different stages of chronic disease of the kidney (CDK) given no therapy replacing renal function (TRRF). MATERIAL AND METHODS:Serum levels of creatinine, electrolytes, parathormone (PTH), 25(OH)-...

journal_title：Terapevticheskii arkhiv

authors： Smirnov AV,Volkov MM,Galkina OV,Zhloba AA,Emanuél' VL

更新日期：2009-01-01 00:00:00

abstract：:The paper discusses the problem of chronic heart failure (CHF) in left ventricular diastolic dysfunction - diastolic heart failure (DHF). It considers whether DHF is an independent phenotype or nothing more than a step in the development of systolic heart failure. The results of a number of studies evaluating the effi...

journal_title：Terapevticheskii arkhiv

authors： Tereshchenko SN,Zhirov IV

更新日期：2009-01-01 00:00:00

abstract：AIM:to define a role of hemostatic disorders in the pathogenesis of Astrakhan rickettsial fever (ARL). SUBJECTS AND METHODS:Platelet functional activity and plasma hemostatic parameters were studied in 89 patients of moderate ARL. RESULTS:The clinical manifestations of hemostatic disorders at the height of ARL were c...

journal_title：Terapevticheskii arkhiv

authors： Maleev VV,Galimzianov KhM,Lazareva EN,Poliakova AM,Astrina OS,Kudriavtsev VA,Arshba TE

更新日期：2009-01-01 00:00:00

abstract：AIM:To estimate a relationship between the intima-media thickness (TIM), cardiovascular risk (CVR) factors, and the level of C-reactive protein (CRP) in gouty patients. SUBJECTS AND METHODS:Eighty-nine patients at an interattack interval were examined. The patients' mean age was 46.0 +/- 11.4 years; the duration of th...

journal_title：Terapevticheskii arkhiv

authors： Il'ina AE,Varfolomeeva EI,Volkov AV,Mach ES,Aleksandrova EN,Novikov AA,Il'inykh EV,Barskova VG,Nasonov EL

更新日期：2009-01-01 00:00:00

abstract：AIM:To study effects of long-term administration of ACE inhibitor ramipril (hartil) on renin-angiotensin-aldosteron system (RAAS), dynamics of clinical symptoms of the disease and structural-functional indices of the right and left ventricle (RV, LI) in patients with chronic obstructive pulmonary disease (COPD) with de...

journal_title：Terapevticheskii arkhiv

authors： Krushka SI,Butorov IV,Butorov SI,Bodrug NI,Tofan EF

更新日期：2008-01-01 00:00:00

abstract：AIM:To assess carotid blood flow in healthy subjects and hypertensive patients, to specify prognostic significance of factors affecting carotid circulation with use of a multivariate analysis. MATERIAL AND METHODS:Clinical examination, ultrasonic dopplerography of the internal carotid arteries (ICA), echocardiography,...

journal_title：Terapevticheskii arkhiv

authors： Rabinovich RM

更新日期：2008-01-01 00:00:00

abstract：AIM:To examine correlations between immunological markers, clinical parameters and MRI data in patients with early rheumatoid arthritis (RA) and undifferentiated arthritis (UDA). MATERIAL AND METHODS:The study was made of 211 patients with early RA (43 males, 168 females) and 47 patients with early UDA (mean age 48.6 ...

journal_title：Terapevticheskii arkhiv

authors： Karateev DE,Aleksandrova EN,Demidova NV,Luchikhina EL,Novikov AA,Pogozheva EIu,Rapoport IE,Smirnov AV,Nasonov EL

更新日期：2008-01-01 00:00:00

abstract：AIM:To study morphofunctional status of neutrophilic polymorphonuclear leukocytes (NPNL) in patients with chronic autoimmune thyroiditis (CAIT). MATERIAL AND METHODS:The morphofunctional status of NPNL was investigated with vital computer phasic morphometry (CPM) in 25 patients (24 females and 1 male, mean age 45.4 +/...

journal_title：Terapevticheskii arkhiv

authors： Rustembekova SA,Ametov AS,Vasilenko IA,Metelin VB

更新日期：2008-01-01 00:00:00

abstract：AIM:To evaluate efficacy of the International Prognostic Index (IPI) in relation to diffuse B-large cell lymphosarcoma (BLCLS), to identify significant prognostic factors. MATERIAL AND METHODS:The trial enrolled 121 patients (67 males and 54 females, mean age 54 years) suffering from BLCLS with involvement of the lymp...

journal_title：Terapevticheskii arkhiv

authors： Magomedova AU,Vorob'ev AI

更新日期：2008-01-01 00:00:00

abstract：AIM:The retrospective analysis of prevalence, peculiarities of duration of biliary calculosis without gall bladder cholesterosis, biliary calculosis with gall-bladder cholesterosis and xanthogranulematous cholecystitis among persons who underwent cholecystectomy using clinical, instrumental and morphological data. MATE...

journal_title：Terapevticheskii arkhiv

authors： Shcherbinina MB,Zakrevskaia EV

更新日期：2008-01-01 00:00:00

abstract：AIM:To study fractional composition of red cell membrane (RCM) lipids in patients with severe iron-deficiency anemia (IDA) complicated by myocardiodystrophy prior to treatment and after 1-month combined treatment with sorbifer and mildronate. MATERIAL AND METHODS:Fatty acid composition of RCM lipids was studied in 12 ...

journal_title：Terapevticheskii arkhiv

authors： Goncharova EV,Govorin AV

更新日期：2008-01-01 00:00:00

abstract：AIM:To elucidate efficacy of a combination almitrine+thiotropium bromide (TB)+pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) of stage II-III complicated with chronic respiratory failure (CRF). MATERIAL AND METHODS:Efficacy of therapy was compared in two groups of patients: group 1 (n = 2...

journal_title：Terapevticheskii arkhiv

authors： Titova ON,Ignat'ev VA,Didur MD,Kameneva MIu,Sukhovskaia OA

更新日期：2008-01-01 00:00:00

abstract：AIM:To study mucous (parietal) gastroduodenal microflora in healthy persons, patients with ulcer and chronic gastritis, to develop diagnostic criteria and classification of gastroduodenal dysbacteriosis. MATERIAL AND METHODS:Biopsy specimens were obtained from gastroduodenal mucosa of 134 patients with ulcer, 36--with...

journal_title：Terapevticheskii arkhiv

authors： Chernin VV,Bondarenko VM,Chervinets VM,Bazlov SN

更新日期：2008-01-01 00:00:00

abstract：AIM:To discover relations between allergic diseases and H. pylori infection in patients with gastroduodenal diseases. MATERIAL AND METHODS:The study was made of 113 patients (age 22-65, 34 males and 79 females) with chronic gastritis and duodenal ulcer. Of them, 60 patients (group 1) had concomitant allergy (urticaria...

journal_title：Terapevticheskii arkhiv

authors： Lazebnik LB,Chernutskaia SP,Gervazieva VB,Sukhareva GV

更新日期：2008-01-01 00:00:00

abstract：AIM:To study efficacy of ANCA-RPGN treatment with corticosteroids and cyclophosphamide or mycophenolic acid drugs. MATERIAL AND METHODS:We treated 28 patients (17 males and 11 females aged 19-71 years) with morphologically verified ANCA-associated crescentic RPGN (crescentic median 79 (63:88)%. The patients received c...

journal_title：Terapevticheskii arkhiv

authors： Tomilina NA,Biriukova LS,Egorova ET,Sukhanov AV,Stoliarevich ES,Kupavtseva OA,Fedorova ND,Frolov AV,Trushkin RN,Kurenkova LG

更新日期：2008-01-01 00:00:00

abstract：AIM:To study hypotensive effectiveness and organ-protective properties of telmisartan in patients with essential hypertension (EH). MATERIAL AND METHODS:The trial enrolled 33 patients with EH of stage II, blood pressure (BP) elevation of the first and second degree, with ultrasound-diagnosed left ventricular (LV) hype...

journal_title：Terapevticheskii arkhiv

authors： Petriĭ VV,Sergushkina NG,Brazhnik VA,Makolkin VI

更新日期：2008-01-01 00:00:00

abstract：AIM:To assess efficacy of vaccine against viral hepatitis B (VHB) in adults after achievement of acute leukemia (AL) remission. MATERIAL AND METHODS:Specific prevention of VHB was made in 30 AL patients with recombinant vaccine Engerix B by two schemes: 0-1-2-12 and 0-1-2-6 months with double adult dose 40 mcg. Effica...

journal_title：Terapevticheskii arkhiv

authors： Gurina NM,Svedentsov EP,Shardakov VI,Cherepanova VV

更新日期：2008-01-01 00:00:00

abstract：AIM:To compare efficacy and tolerability of combined therapy with methotrexate (MTX), sulfasalazine (SSZ) and hydroxychloroquine (HCQ) with MTX-monotherapy in patients with rheumatoid arthritis (RA). MATERIAL AND METHODS:RA patients (n = 60) who had not been treated with the above drugs were randomized (1:1) to receiv...

journal_title：Terapevticheskii arkhiv

authors： Gubar' EE,Bochkova AG,Bunchuk NV

更新日期：2008-01-01 00:00:00

abstract：AIM:To detect specific morphological signs of hepatic lesion in patients with cholesterosis of the gall bladder and atherogenic dyslipidemia in the presence of steatohepatitis. MATERIAL AND METHODS:Atherogenic dyslipidemia was detected in 150 patients with steatohepatitis. Ultrasound investigation diagnosed cholestero...

journal_title：Terapevticheskii arkhiv

authors： Lazebnik LB,Ovsiannikova ON,Zvenigorodskaia LA,Mel'nikova NV,Samsonova NG,Khomeriki SG

更新日期：2008-01-01 00:00:00

abstract：AIM:To review diagnostic approaches in chronic diseases of the small intestine. MATERIAL AND METHODS:A total of 1096 patients with chronic diseases of the small intestine were admitted to the clinic of the Central Research Institute of Gastroenterological Diseases in 1987-2006. RESULTS:Most of the patients (90.5%) ha...

journal_title：Terapevticheskii arkhiv

authors： Parfenov AI,Krums LM,Sivash ES,Tsaregorodtseva TM,Poleva NI,Ruchkina IN,Sabel'nikova EA,Chikunova BZ

更新日期：2008-01-01 00:00:00

abstract：AIM:To examine effects of endotheline-1 (ET-1) and nitric oxide (NO) on endothelium-dependent mechanisms of vascular tonicity regulation in patients with chronic cardiac failure (CCF) of FC I-IV (NYHA). MATERIAL AND METHODS:Vascular reactions of 94 patients with CCF of FC I-IV were examined according to D.S. Celermaje...

journal_title：Terapevticheskii arkhiv

authors： Denisov EN,Kots IaI,Bakhtiiarov RZ,Gumanova NG

更新日期：2007-01-01 00:00:00

abstract：AIM:To characterize the spectrum, incidence rate and features of pulmonary pathology in HIV-infected inpatients with reference to a fall in the count of CD4-lymphocytes. MATERIAL AND METHODS:A total of 2370 patients with HIV infection admitted to Moscow infectious hospital N 2 were examined. The protocol of examinatio...

journal_title：Terapevticheskii arkhiv

authors： Vasil'eva TE,Litvinova NG,Shakhgil'dian VI,Ol'shankiĭ AIa,Filippov PG,Morozova SV,Kravchenko AV,Gruzdev BM,Danilova TV

更新日期：2007-01-01 00:00:00

abstract：AIM:To test feasibility of transplantation of hemopoietic stem cells (THSC) with conditioning in low-intensity regimen associated with minimal toxic complications and engraftment in patients with hematological malignancy (HM) from a high risk group. MATERIAL AND METHODS:THSC was performed in 33 patients aged 18 to 65 ...

journal_title：Terapevticheskii arkhiv

authors： Demidova IA,Parovichnikova EN,Kut'ina RM,Poreshina LP,Shpakova AP,Ol'shanskaia IuV,Misiurin AV,Savchenko VG

更新日期：2007-01-01 00:00:00

abstract：AIM:To study vascular endothelium in patients with systemic vasculitis (SV) with non-invasive methods. MATERIAL AND METHODS:A total of 65 SV patients entered the trial: 20 patients with Henoch-Schonlein purpura (HSP), 20 patients with thromboangitis obliterans (TO), 10 patients with polyarteritis nodosa (PN), 15 patie...

journal_title：Terapevticheskii arkhiv

authors： Shilkina NP,Vinogradov AA

更新日期：2007-01-01 00:00:00

abstract：AIM:To study efficacy of the myocardial cytoprotector trimethasidine MB and metabolic drug 3-(2,2,2-trimethylhydrasine) propionate dihydrate (3-TMHP) in the treatment of chronic cardiac failure (CCF). MATERIAL AND METHODS:Sixty-five patients with CCF after myocardial infarction (> 6 months) with left ventricular eject...

journal_title：Terapevticheskii arkhiv

authors： Vasiuk IuA,Iushchuk EN,Shkol'nik EL,Khadzegova AB,Sadulaeva IA,Vit'ko NK,Vakhromeeva MN

更新日期：2007-01-01 00:00:00

abstract：AIM:To compare efficacy of avelox systemic antibiotic therapy with and without maxillary puncture in acute purulent rhinosinusitis (ARS). MATERIAL AND METHODS:A total of 40 ARS patients were divided into two groups: puncture was not made in 20 patients of the study group and was made in 20 patients of the control grou...

journal_title：Terapevticheskii arkhiv

authors： Ivanchenko OA,Chuchueva NG,Lopatin AS

更新日期：2007-01-01 00:00:00

abstract：AIM:To investigate effects of polymorphic variants of surfactant protein C gene (SFTPC) on the course of the disease in patients with chronic obstructive pulmonary disease (COPD). MATERIAL AND METHODS:Sixty COPD patients were examined with COPD of stage 0-IV. The following parameters were studied: smoking index (SI), ...

journal_title：Terapevticheskii arkhiv

authors： Tsvetkova OA,Veselovskaia MV

更新日期：2007-01-01 00:00:00

abstract：AIM:To assess efficacy and safety of selective beta-adrenoblockers (BAB) metoprolol succinate and nebivolol in patients with arterial hypertension (AH) and/or IHD associated with bronchoobstructive syndrome (BOS). MATERIAL AND METHODS:Fifty patients suffering from AH and/or IHD associated with BOS in chronic obstructi...

journal_title：Terapevticheskii arkhiv

authors： Ovcharenko SI,Litvinova IV,Mikolkin VI

更新日期：2007-01-01 00:00:00

abstract：AIM:To evaluate long-term therapeutic effect and safety of structum in patients with manifest coxarthrosis. MATERIAL AND METHODS:Twenty patients with manifest coxarthrosis of degree I-III were given a 6 month structum course. Criteria of efficacy were Leken index, pain in the affected joints, nonsteroid anti-inflammat...

journal_title：Terapevticheskii arkhiv

authors： Shmidt EI,Bilinskaia MA,Belozerova IV,Soldatov DG,Dmitrieva ME

更新日期：2007-01-01 00:00:00

abstract：AIM:To study prevalence of arterial hypertension (AH) in relation to gender, age, profession, risk factors (RF), RF combination; efficacy of active long-term multifactor prevention among the employees of industrial enterprises in some regions of Russia. MATERIAL AND METHODS:14000 males and 20969 females from industria...

journal_title：Terapevticheskii arkhiv

authors： Tozhiev MS,Khvan YE,Shestov DB,Tadzhiev FS,Vorob'ev AM,Ochilova RKh,Terebov AA,Avdeeva GP,Bondarenko VV,Tepliakov VCh

更新日期：2007-01-01 00:00:00

abstract：AIM:To study effects of two hypotensive drugs--normodipin and spirapril--on intravascular activity of platelets in patients with metabolic syndrome (MS). MATERIAL AND METHODS:Normodipin was given to 25 patients with MS for 3 months, spirapril--to 20 patients for 3 months. The effect was evaluated by changes in lipid p...

journal_title：Terapevticheskii arkhiv

authors： Medvedev IN

更新日期：2007-01-01 00:00:00

abstract：AIM:To evaluate a combination of the effects of non-drug measures and rozuvastatin on the lipid spectrum and blood pressure (BP) in patients with treated arterial hypertension (AH) concurrent with dyslipidemia. MATERIALS AND METHODS:The multicenter open-labeled prospective program included 299 patients from 19 cities ...

journal_title：Terapevticheskii arkhiv

authors： Chazova IE,Kukharchuk VV,Ratova LG,Kaminnaia VI

更新日期：2007-01-01 00:00:00

abstract：AIM:To study the levels of inflammatory markers in acute coronary syndrome (ACS) and 6 months after its regression in patients with diabetes mellitus (DM) type 2; to evaluate effects of anxiodepressive disorders on inflammatory markers. MATERIAL AND METHODS:The levels of high-sensitive C-reactive protein (hsCRP), inte...

journal_title：Terapevticheskii arkhiv

authors： Chazova TE,Masenko VP,Zykov KA,Golitsyna TIu

更新日期：2007-01-01 00:00:00

abstract：AIM:To evaluate contribution of endothelial dysfunction and impairment of endothelial proliferation/ regeneration to mechanisms of development of tubulointerstitial fibrosis (TIF) in chronic glomerulonephritis (CGN) basing on urinary levels of markers of endothelial activation/impairment and angiogenesis factors. MATE...

journal_title：Terapevticheskii arkhiv

authors： Bobkova IN,Kozlovskaia LV,Rameeva AS,Varshavskiĭ VA,Golitsyna EP

更新日期：2007-01-01 00:00:00